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Cytokeratin 14 Rabbit mAb
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- BACKGROUND
Application 
| WB, IHC-P, FC, IP, ICC |
|---|---|
| Primary Accession | P02533 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 51561 Da |
| Gene ID | 3861 |
|---|---|
| Other Names | KRT14 |
| Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 |
| Format | Liquid |
| Name | KRT14 |
|---|---|
| Function | The nonhelical tail domain is involved in promoting KRT5- KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. |
| Cellular Location | Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern. |
| Tissue Location | Expressed in the corneal epithelium (at protein level) (PubMed:26758872). Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair (PubMed:9457912). Found in keratinocytes surrounding the club hair during telogen (PubMed:9457912). |
Research Areas
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