Wnt2 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P09544 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 40418 Da |
Gene ID | 7472 |
---|---|
Other Names | WNT2 |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | WNT2 |
---|---|
Synonyms | INT1L1, IRP |
Function | Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:20018874). Functions as a upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). |
Cellular Location | Secreted, extracellular space, extracellular matrix. Secreted |
Tissue Location | Expressed in brain in the thalamus, in fetal and adult lung and in placenta. |
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