p57 Kip2 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IP, ICC |
---|---|
Primary Accession | P49918 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 32177 Da |
Gene ID | 1028 |
---|---|
Other Names | CDKN1C |
Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 IF~~1/50-1/200 |
Format | Liquid |
Name | CDKN1C |
---|---|
Synonyms | KIP2 |
Function | Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver |
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