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Ferritin Heavy Chain Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P02794 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 21226 Da |
| Gene ID | 2495 |
|---|---|
| Other Names | FTH1 |
| Dilution | WB~~1/500-1/1000 |
| Format | Liquid |
| Name | FTH1 |
|---|---|
| Synonyms | FTH, FTHL6 |
| Function | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity (PubMed:9003196). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed:9003196). Also plays a role in delivery of iron to cells (By similarity). Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (PubMed:24695223, PubMed:26436293). |
| Cellular Location | Cytoplasm. Lysosome. Cytoplasmic vesicle, autophagosome |
| Tissue Location | Expressed in the liver. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
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$ 350.00
Cat# AP77173
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