AACT Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IP, ICC |
---|---|
Primary Accession | P01011 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 47651 Da |
Gene ID | 12 |
---|---|
Other Names | SERPINA3 |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | SERPINA3 |
---|---|
Synonyms | AACT |
Function | Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. |
Cellular Location | Secreted. |
Tissue Location | Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains. |
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