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HMGCS2 Rabbit mAb
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- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P54868 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 56635 Da |
| Gene ID | 3158 |
|---|---|
| Other Names | HMGCS2 |
| Dilution | WB~~1/500-1/1000 |
| Format | Liquid |
| Name | HMGCS2 |
|---|---|
| Function | Catalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate. |
| Cellular Location | Mitochondrion {ECO:0000250|UniProtKB:P22791}. |
| Tissue Location | Expression in liver is 200-fold higher than in any other tissue. Low expression in colon, kidney, testis, and pancreas Very low expression in heart and skeletal muscle (PubMed:16940161, PubMed:21952825, PubMed:7893153). Not detected in brain (PubMed:21952825). |
Research Areas
Citations (0)
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Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP77000
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