PBK Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, IP |
---|---|
Primary Accession | Q96KB5 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 36085 Da |
Gene ID | 55872 |
---|---|
Other Names | PBK |
Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 IP~~1/20 |
Format | Liquid |
Name | PBK |
---|---|
Synonyms | TOPK |
Function | Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin- induced DNA damage. |
Tissue Location | Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules. |

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