Paxillin Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IP |
---|---|
Primary Accession | P49023 |
Reactivity | Human, Rat, Hamster |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 64505 Da |
Gene ID | 5829 |
---|---|
Other Names | PXN |
Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 IP~~1/20 |
Format | Liquid |
Name | PXN |
---|---|
Function | Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Recruits other proteins such as TRIM15 to focal adhesion. |
Cellular Location | Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q8VI36}. Note=Colocalizes with integrins at the cell periphery. Colocalize with PXN to membrane ruffles and the leading edge of migrating cells (PubMed:23128389). {ECO:0000250, ECO:0000269|PubMed:23128389} |
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