Syntaxin Binding Protein 1 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P61764 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 67569 Da |
Gene ID | 6812 |
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Other Names | STXBP1 |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | STXBP1 |
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Synonyms | UNC18A |
Function | Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins (By similarity). Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. Involved in the release of neurotransmitters from neurons through interacting with SNARE complex component STX1A and mediating the assembly of the SNARE complex at synaptic membranes (By similarity). May play a role in determining the specificity of intracellular fusion reactions. |
Cellular Location | Cytoplasm, cytosol. Membrane; Peripheral membrane protein |
Tissue Location | Brain and spinal cord. Highly enriched in axons. |
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