MGMT Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP |
---|---|
Primary Accession | P16455 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 21646 Da |
Gene ID | 4255 |
---|---|
Other Names | MGMT |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | MGMT |
---|---|
Function | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. |
Cellular Location | Nucleus. |
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