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Glutathione Peroxidase 1 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IP, ICC |
|---|---|
| Primary Accession | P07203 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 22088 Da |
| Gene ID | 2876 |
|---|---|
| Other Names | GPX1 |
| Dilution | WB~~1/500-1/1000 IF~~1/50-1/200 IP~~1/20 |
| Format | Liquid |
| Name | GPX1 (HGNC:4553) |
|---|---|
| Function | Catalyzes the reduction of hydroperoxides in a glutathione- dependent manner thus regulating cellular redox homeostasis (PubMed:11115402, PubMed:36608588). Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides (PubMed:11115402, PubMed:36608588). In platelets catalyzes the reduction of 12-hydroperoxyeicosatetraenoic acid, the primary product of the arachidonate 12-lipoxygenase pathway (PubMed:11115402). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P11352}. Mitochondrion {ECO:0000250|UniProtKB:P11352} |
| Tissue Location | Expressed in platelets (at protein level). |
Research Areas
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$ 385.00
Cat# AP76512
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