14-3-3 gamma Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P61981 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 28303 Da |
Gene ID | 7532 |
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Other Names | YWHAG |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | YWHAG (HGNC:12852) |
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Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways (PubMed:15696159, PubMed:16511572, PubMed:36732624). Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif (PubMed:15696159, PubMed:16511572, PubMed:36732624). Binding generally results in the modulation of the activity of the binding partner (PubMed:16511572). Promotes inactivation of WDR24 component of the GATOR2 complex by binding to phosphorylated WDR24 (PubMed:36732624). Participates in the positive regulation of NMDA glutamate receptor activity by promoting the L- glutamate secretion through interaction with BEST1 (PubMed:29121962). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P68252}. |
Tissue Location | Highly expressed in brain, skeletal muscle, and heart. |
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