von Willebrand Factor Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | P04275 |
Reactivity | Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 309265 Da |
Gene ID | 7450 |
---|---|
Other Names | VWF |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | VWF |
---|---|
Synonyms | F8VWF |
Function | Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. |
Cellular Location | Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules |
Tissue Location | Plasma. |
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