UCHL5 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP, ICC |
---|---|
Primary Accession | Q9Y5K5 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 37607 Da |
Gene ID | 51377 |
---|---|
Other Names | UCHL5 |
Dilution | WB~~1/500-1/1000 IF~~1/50-1/200 IP~~1/20 |
Format | Liquid |
Name | UCHL5 |
---|---|
Synonyms | UCH37 |
Function | Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1. |
Cellular Location | Cytoplasm. Nucleus. Note=Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus |
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