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U1C Rabbit mAb
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Application 
| WB, IHC-P, IHC-F, IP, ICC |
|---|---|
| Primary Accession | P09234 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 17394 Da |
| Gene ID | 6631 |
|---|---|
| Other Names | SNRPC |
| Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 |
| Format | Liquid |
| Name | SNRPC {ECO:0000255|HAMAP-Rule:MF_03153} |
|---|---|
| Function | Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. |
| Cellular Location | Nucleus {ECO:0000255|HAMAP-Rule:MF_03153, ECO:0000269|PubMed:2136774} |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP76221
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