Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
Cyclin B1 Antibody (S126)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P14635 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 48337 Da |
| Antigen Region | 104-133 aa |
| Gene ID | 891 |
|---|---|
| Other Names | G2/mitotic-specific cyclin-B1, CCNB1, CCNB |
| Target/Specificity | This Cyclin B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from human Cyclin B1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Cyclin B1 Antibody (S126) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CCNB1 |
|---|---|
| Synonyms | CCNB |
| Function | Essential for the control of the cell cycle at the G2/M (mitosis) transition. |
| Cellular Location | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome |
Provided below are standard protocols that you may find useful for product applications.
Background
Cyclin B1 is a regulatory protein involved in mitosis. It complexes with p34(cdc2) to form the maturation-promoting factor (MPF).
References
Yoshida, T., et al., Ann. Oncol. 15(2):252-256 (2004). Chang, D.C., et al., J. Biol. Chem. 278(39):37865-37873 (2003). Sanchez, V., et al., J. Virol. 77(24):13214-13224 (2003). Li, J.Q., et al., Int. J. Oncol. 22(5):1101-1110 (2003). Porter, L.A., et al., Blood 101(5):1928-1933 (2003).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
