Proteasome beta 9 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC |
---|---|
Primary Accession | P28065 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 23264 Da |
Gene ID | 5698 |
---|---|
Other Names | PSMB9 |
Dilution | WB~~1/500-1/1000 IF~~1/50-1/200 |
Format | Liquid |
Name | PSMB9 |
---|---|
Synonyms | LMP2, PSMB6i, RING12 |
Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (PubMed:33727065, PubMed:34819510). The proteasome has an ATP- dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. |
Cellular Location | Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809}. Nucleus |
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