Periostin Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, IP |
---|---|
Primary Accession | Q15063 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 93314 Da |
Gene ID | 10631 |
---|---|
Other Names | POSTN |
Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 |
Format | Liquid |
Name | POSTN |
---|---|
Synonyms | OSF2 |
Function | Induces cell attachment and spreading and plays a role in cell adhesion (PubMed:12235007). Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity). |
Cellular Location | Golgi apparatus {ECO:0000250|UniProtKB:Q62009}. Secreted Secreted, extracellular space, extracellular matrix Note=Colocalizes with BMP1 in the Golgi {ECO:0000250|UniProtKB:Q62009} |
Tissue Location | Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus, thyroid tissue and breast. Expressed in the kidney (PubMed:21763681). Expressed in the lung (PubMed:22079858). Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor Overexpressed in breast cancers. |

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