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p150 CAF1 Rabbit mAb
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Application 
| WB, IHC-P, IHC-F, IP, ICC |
|---|---|
| Primary Accession | Q13111 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 106910 Da |
| Gene ID | 10036 |
|---|---|
| Other Names | CHAF1A |
| Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 IF~~1/50-1/200 |
| Format | Liquid |
| Name | CHAF1A (HGNC:1910) |
|---|---|
| Synonyms | CAF, CAF1P150 |
| Function | Acts as a component of the histone chaperone complex chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto DNA during replication and repair. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci. |
| Cellular Location | Nucleus. Note=DNA replication foci |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP75846
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