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MAPK6 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IP |
|---|---|
| Primary Accession | Q16659 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 82681 Da |
| Gene ID | 5597 |
|---|---|
| Other Names | MAPK6 |
| Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 |
| Format | Liquid |
| Name | MAPK6 |
|---|---|
| Synonyms | ERK3, PRKM6 |
| Function | Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity). |
| Cellular Location | Cytoplasm. Nucleus. Note=Translocates to the cytoplasm following interaction with MAPKAPK5 |
| Tissue Location | Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts |
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP75691
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