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FARSA Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9Y285 |
| Other Accession | Q505J8, Q8C0C7 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 57564 Da |
| Antigen Region | 54-83 aa |
| Gene ID | 2193 |
|---|---|
| Other Names | Phenylalanine--tRNA ligase alpha subunit, CML33, Phenylalanyl-tRNA synthetase alpha subunit, PheRS, FARSA, FARS, FARSL, FARSLA |
| Target/Specificity | This FARSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the N-terminal region of human FARSA. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FARSA Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FARSA |
|---|---|
| Synonyms | FARS, FARSL, FARSLA |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q505J8}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARSA is similar to the catalytic subunit of prokaryotic and Saccharomyces cerevisiae phenylalanyl-tRNA synthetases (PheRS). This protein has been shown to be expressed in a tumor-selective and cell cycle stage- and differentiation-dependent manner, the first member of the tRNA synthetase gene family shown to exhibit this type of regulated expression.
References
Gevaert,K., Nat. Biotechnol. 21 (5), 566-569 (2003)
Moor,N.,Protein Expr. Purif. 24 (2), 260-267 (2002)
Sen,S., Proc. Natl. Acad. Sci. U.S.A. 94 (12), 6164-6169 (1997)
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