IL-1 Receptor Antagonist Protein Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IP, ICC |
---|---|
Primary Accession | P18510 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 20055 Da |
Gene ID | 3557 |
---|---|
Other Names | IL1RN |
Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 IF~~1/50-1/200 |
Format | Liquid |
Name | IL1RN |
---|---|
Synonyms | IL1F3, IL1RA |
Function | Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens. |
Cellular Location | [Isoform 1]: Secreted [Isoform 3]: Cytoplasm. |
Tissue Location | The intracellular form of IL1RN is predominantly expressed in epithelial cells |
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