Aspartate Aminotransferase Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IP |
---|---|
Primary Accession | P00505 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 47518 Da |
Gene ID | 2806 |
---|---|
Other Names | GOT2 |
Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 |
Format | Liquid |
Name | GOT2 (HGNC:4433) |
---|---|
Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids. |
Cellular Location | Mitochondrion matrix. Cell membrane. Note=Exposure to alcohol promotes translocation to the cell membrane. |
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