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EpCAM Rabbit mAb
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- BACKGROUND
Application 
| WB, IHC-P, IHC-F, IP, ICC |
|---|---|
| Primary Accession | P16422 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 34932 Da |
| Gene ID | 4072 |
|---|---|
| Other Names | EPCAM |
| Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 IF~~1/50-1/200 |
| Format | Liquid |
| Name | EPCAM |
|---|---|
| Synonyms | GA733-2, M1S2, M4S1, MIC18, TACSTD1, TRO |
| Function | May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. |
| Cellular Location | Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction |
| Tissue Location | Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC) Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP75406
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