DBF4 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
---|---|
Primary Accession | Q9UBU7 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 76858 Da |
Gene ID | 10926 |
---|---|
Other Names | DBF4 |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | DBF4 |
---|---|
Synonyms | ASK, DBF4A, ZDBF1 |
Function | Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7- DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. |
Cellular Location | Nucleus. |
Tissue Location | Highly expressed in testis and thymus. Expressed also in most cancer cells lines. |

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