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> home > Products > Primary Antibodies > Antibody Collections > Phospho Antibodies > Phospho-CREB (Ser133) Rabbit mAb
Phospho-CREB (Ser133) Rabbit mAb
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Application 
| WB, IHC-P, IP |
|---|---|
| Primary Accession | P16220 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 35136 Da |
| Gene ID | 1385 |
|---|---|
| Other Names | CREB1 |
| Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 IP~~1/20 |
| Format | Liquid |
| Name | CREB1 |
|---|---|
| Function | Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters (By similarity). Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation (PubMed:14536081). Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells (By similarity). Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00312, ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12552083} |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP75290
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