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Bak Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IP |
|---|---|
| Primary Accession | Q16611 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 23409 Da |
| Gene ID | 578 |
|---|---|
| Other Names | BAK1 |
| Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 |
| Format | Liquid |
| Name | BAK1 |
|---|---|
| Synonyms | BAK, BCL2L7, CDN1 |
| Function | Plays a role in the mitochondrial apoptotic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases. |
| Cellular Location | Mitochondrion outer membrane; Single-pass membrane protein |
| Tissue Location | Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP75143
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