ENO1 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IP, ICC |
---|---|
Primary Accession | P06733 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 47169 Da |
Gene ID | 2023 |
---|---|
Other Names | ENO1 |
Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 IF~~1/50-1/200 IP~~1/20 |
Format | Liquid |
Name | ENO1 |
---|---|
Synonyms | ENO1L1, MBPB1, MPB1 |
Function | Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (PubMed:1369209, PubMed:29775581). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses (PubMed:10802057, PubMed:12666133, PubMed:2005901, PubMed:29775581). May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (PubMed:12666133). Stimulates immunoglobulin production (PubMed:1369209). |
Cellular Location | Cytoplasm. Cell membrane. Cytoplasm, myofibril, sarcomere, M line. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. ENO1 is localized to the M line |
Tissue Location | The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons |
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