ZHX2 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC |
---|---|
Primary Accession | Q9Y6X8 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 92307 Da |
Gene ID | 22882 |
---|---|
Other Names | ZHX2 |
Dilution | WB~~1/500-1/1000 IF~~1/50-1/200 |
Format | Liquid |
Name | ZHX2 |
---|---|
Synonyms | AFR1, KIAA0854, RAF |
Function | Acts as a transcriptional repressor (PubMed:12741956). Represses the promoter activity of the CDC25C gene stimulated by NFYA (PubMed:12741956). May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (By similarity). In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:12741956, ECO:0000269|PubMed:17056598} Note=Colocalizes with EFNB1 intracellular domain in the nucleus {ECO:0000250|UniProtKB:Q8C0C0} |
Tissue Location | Ubiquitously expressed. Expressed in podocytes. |
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