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CD13 Rabbit mAb
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Application 
| WB, IHC-P, IHC-F, IP, ICC |
|---|---|
| Primary Accession | P15144 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 109540 Da |
| Gene ID | 290 |
|---|---|
| Other Names | ANPEP |
| Dilution | WB~~1/500-1/1000 IHC~~1/50-1/100 IF~~1/50-1/200 |
| Format | Liquid |
| Name | ANPEP |
|---|---|
| Synonyms | APN, CD13, PEPN |
| Function | Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity (By similarity). |
| Cellular Location | Cell membrane; Single-pass type II membrane protein. Note=Also found as a soluble form |
| Tissue Location | Expressed in epithelial cells of the kidney, intestine, and respiratory tract; granulocytes, monocytes, fibroblasts, endothelial cells, cerebral pericytes at the blood-brain barrier, synaptic membranes of cells in the CNS. Also expressed in endometrial stromal cells, but not in the endometrial glandular cells. Found in the vasculature of tissues that undergo angiogenesis and in malignant gliomas and lymph node metastases from multiple tumor types but not in blood vessels of normal tissues. A soluble form has been found in plasma. It is found to be elevated in plasma and effusions of cancer patients. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP74875
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