PD L2 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q9BQ51 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 30957 Da |
Gene ID | 80380 |
---|---|
Other Names | PDCD1LG2 |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | PDCD1LG2 |
---|---|
Synonyms | B7DC, CD273, PDCD1L2, PDL2 |
Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). |
Cellular Location | [Isoform 3]: Secreted [Isoform 1]: Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9WUL5, ECO:0000305|PubMed:15340161} |
Tissue Location | Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus |
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