APOA2 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | P02652 |
Other Accession | P18656 |
Reactivity | Human |
Predicted | Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 11175 Da |
Antigen Region | 28-56 aa |
Gene ID | 336 |
---|---|
Other Names | Apolipoprotein A-II, Apo-AII, ApoA-II, Apolipoprotein A2, Proapolipoprotein A-II, ProapoA-II, Truncated apolipoprotein A-II, Apolipoprotein A-II(1-76), APOA2 |
Target/Specificity | This APOA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the Central region of human APOA2. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | APOA2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | APOA2 |
---|---|
Function | May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. |
Cellular Location | Secreted. |
Tissue Location | Plasma; synthesized in the liver and intestine. |
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Provided below are standard protocols that you may find useful for product applications.
Background
APOA2, apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.
References
Duesing,K., BMC Med. Genet. 10, 13 (2009)
Atta,M., Thromb. Haemost. 100 (3), 391-396 (2008)
Blanco-Vaca,F., J. Lipid Res. 42 (11), 1727-1739 (2001)
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