COL17A1 Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
---|---|
Primary Accession | Q9UMD9 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 150419 Da |
Gene ID | 1308 |
---|---|
Other Names | COL17A1 BP180 BPAG2 |
Dilution | WB~~WB 1:500-2000, ELISA 1:10000-20000 |
Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
Storage Conditions | -20℃ |
Name | COL17A1 |
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Synonyms | BP180, BPAG2 |
Function | May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. |
Cellular Location | Cell junction, hemidesmosome. Membrane; Single- pass type II membrane protein. Note=Localized along the plasma membrane of the hemidesmosome [97 kDa linear IgA disease antigen]: Secreted, extracellular space, extracellular matrix, basement membrane Note=Localized in the lamina lucida beneath the hemidesmosomes |
Tissue Location | Detected in skin (PubMed:8618013). In the cornea, it is detected in the epithelial basement membrane, the epithelial cells, and at a lower level in stromal cells (at protein level) (PubMed:25676728). Stratified squamous epithelia. Found in hemidesmosomes. Expressed in cornea, oral mucosa, esophagus, intestine, kidney collecting ducts, ureter, bladder, urethra and thymus but is absent in lung, blood vessels, skeletal muscle and nerves |

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Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.

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