Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
KLF5 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, FC, IHC-P, E |
|---|---|
| Primary Accession | Q13887 |
| Other Accession | Q9Z0Z7 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 50792 Da |
| Antigen Region | 341-370 aa |
| Gene ID | 688 |
|---|---|
| Other Names | Krueppel-like factor 5, Basic transcription element-binding protein 2, BTE-binding protein 2, Colon krueppel-like factor, GC-box-binding protein 2, Intestinal-enriched krueppel-like factor, Transcription factor BTEB2, KLF5, BTEB2, CKLF, IKLF |
| Target/Specificity | This KLF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human KLF5. |
| Dilution | IF~~1:10~50 WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KLF5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KLF5 |
|---|---|
| Synonyms | BTEB2, CKLF, IKLF |
| Function | Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes. |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed only in testis and placenta. |
Provided below are standard protocols that you may find useful for product applications.
Background
KLF5 is a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, the protein is thought to be a transcription factor.
References
Guo,P., Dong,X.Y. J. Biol. Chem. 284 (10), 6071-6078 (2009)
Lee,M.Y., Moon,J.S. Biochem. J. 417 (1), 313-322 (2009)
Du,J.X., Bialkowska,A.B. J. Biol. Chem. 283 (46), 31991-32002 (2008)
Miyamoto,S., Suzuki,T. Mol. Cell. Biol. 23 (23), 8528-8541 (2003)
Shi,H., Zhang,Z. Nucleic Acids Res. 27 (24), 4807-4815 (1999)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
