PITX1 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC, IHC-P, E |
---|---|
Primary Accession | P78337 |
Other Accession | P52906, O18400, Q9I8K3, Q6QU75, Q9PWR3, Q9R0W1, P97474, Q99697, Q9W5Z2, O93385, Q9W751, Q99NA7, P70314, P56673 |
Reactivity | Human |
Predicted | Chicken, Mouse, Rat, Xenopus, Zebrafish, Drosophila, C.Elegans |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 34128 Da |
Antigen Region | 123-150 aa |
Gene ID | 5307 |
---|---|
Other Names | Pituitary homeobox 1, Hindlimb-expressed homeobox protein backfoot, Homeobox protein PITX1, Paired-like homeodomain transcription factor 1, PITX1, BFT, PTX1 |
Target/Specificity | This PITX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-150 amino acids from the Central region of human PITX1. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PITX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PITX1 |
---|---|
Synonyms | BFT, PTX1 |
Function | Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. |
Cellular Location | Nucleus. |

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Provided below are standard protocols that you may find useful for product applications.
Background
PITX1 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.
References
Grimminger,P., Ling,F.C. Anticancer Res. 29 (4), 1281-1286 (2009)
Gurnett,C.A., Alaee,F. Am. J. Hum. Genet. 83 (5), 616-622 (2008)
Philippi,A., Tores,F. BMC Med. Genet. 8, 74 (2007)
Shang,J., Li,X. Genomics 40 (1), 108-113 (1997)

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