PDP2 Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9P2J9 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 59978 Da |
Gene ID | 57546 |
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Other Names | PDP2; KIAA1348; [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial; PDP 2; Pyruvate dehydrogenase phosphatase catalytic subunit 2; PDPC 2 |
Dilution | WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
Storage Conditions | -20℃ |
Name | PDP2 (HGNC:30263) |
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Synonyms | KIAA1348 |
Function | Mitochondrial enzyme that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (PDC), thereby stimulating the conversion of pyruvate into acetyl-CoA (By similarity). Acts as a crucial regulator of T cell metabolism and function, with a particular focus on T-helper Th17 (By similarity). |
Cellular Location | Mitochondrion {ECO:0000250|UniProtKB:O88484}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
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