ZP1 Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | P60852 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 70049 Da |
Gene ID | 22917 |
---|---|
Other Names | ZP1; Zona pellucida sperm-binding protein 1; Zona pellucida glycoprotein 1; Zp-1 |
Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
Storage Conditions | -20℃ |
Name | ZP1 |
---|---|
Function | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida. |
Cellular Location | [Processed zona pellucida sperm-binding protein 1]: Zona pellucida |
Tissue Location | Expressed in oocytes (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida.
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