Ribosomal Protein L10L Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P |
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Primary Accession | Q96L21 |
Reactivity | Human, Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 24519 Da |
Gene ID | 140801 |
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Other Names | RPL10L; 60S ribosomal protein L10-like |
Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
Storage Conditions | -20℃ |
Name | RPL10L {ECO:0000303|PubMed:12490704, ECO:0000312|HGNC:HGNC:17976} |
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Function | Testis-specific component of the ribosome, which is required for the transition from prophase to metaphase in male meiosis I (By similarity). Compensates for the inactivated X-linked RPL10 paralog during spermatogenesis (PubMed:12490704). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:25901680, PubMed:32669547). The male germ cell-specific ribosome displays a ribosomal polypeptide exit tunnel of distinct size and charge states compared with the classical ribosome (By similarity). It is responsible for regulating the biosynthesis and folding of a subset of male germ-cell-specific proteins that are essential for the formation of sperm (By similarity). |
Cellular Location | Cytoplasm |
Tissue Location | Almost testis-specific (PubMed:12490704, PubMed:19333399, PubMed:28502657). Also expressed in pre- and postmenopausal ovary (PubMed:19333399). |

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Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in compensating for the inactivated X- linked gene during spermatogenesis.

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