Rab 20 Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q9NX57 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 26277 Da |
Gene ID | 55647 |
---|---|
Other Names | RAB20; Ras-related protein Rab-20 |
Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
Storage Conditions | -20℃ |
Name | RAB20 |
---|---|
Function | Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. |
Cellular Location | Golgi apparatus. Cytoplasmic vesicle, phagosome Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211) {ECO:0000250|UniProtKB:P35295, ECO:0000269|PubMed:21255211} |
Tissue Location | Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
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