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CSNK2B Antibody (C-term F168)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P67870 |
| Other Accession | P28021, P67874, P67873, P67872, P67871, Q91398, P67869, P67868 |
| Reactivity | Human |
| Predicted | Bovine, Chicken, Zebrafish, Mouse, Pig, Rabbit, Rat, Xenopus |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 24942 Da |
| Antigen Region | 153-184 aa |
| Gene ID | 1460 |
|---|---|
| Other Names | Casein kinase II subunit beta, CK II beta, Phosvitin, Protein G5a, CSNK2B, CK2N, G5A |
| Target/Specificity | This CSNK2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-184 amino acids from the C-terminal region of human CSNK2B. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CSNK2B Antibody (C-term F168) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CSNK2B (HGNC:2460) |
|---|---|
| Synonyms | CK2N, G5A |
| Function | Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (PubMed:11239457, PubMed:16818610). Participates in Wnt signaling (By similarity). |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
CSNK2B is the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
References
Schwartz, E.I., et al., Mol. Cell. Biol. 24(21):9580-9591 (2004).
Lee, G., et al., J. Biol. Chem. 279(8):6834-6839 (2004).
Lim, A.C., et al., J. Biol. Chem. 279(6):4433-4439 (2004).
Singh, D.K., et al., Virology 313(2):435-451 (2003).
Szebeni, A., et al., J. Biol. Chem. 278(11):9107-9115 (2003).
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