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Ikaros 3 Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9UKT9 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 58023 Da |
| Gene ID | 22806 |
|---|---|
| Other Names | IKZF3; ZNFN1A3; Zinc finger protein Aiolos; Ikaros family zinc finger protein 3 |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
| Name | IKZF3 |
|---|---|
| Synonyms | ZNFN1A3 |
| Function | Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner. |
| Cellular Location | Nucleus. Cytoplasm [Isoform 3]: Nucleus [Isoform 14]: Nucleus. Cytoplasm |
| Tissue Location | Expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2- dependent manner.
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