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Cdc7 Polyclonal Antibody
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- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | O00311 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 63888 Da |
| Gene ID | 8317 |
|---|---|
| Other Names | CDC7; CDC7L1; Cell division cycle 7-related protein kinase; CDC7-related kinase; HsCdc7; huCdc7 |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
| Name | CDC7 (HGNC:1745) |
|---|---|
| Synonyms | CDC7L1 |
| Function | Kinase involved in initiation of DNA replication. Phosphorylates critical substrates that regulate the G1/S phase transition and initiation of DNA replication, such as MCM proteins and CLASPIN. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.
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