ECE-1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| FC, IHC-P, WB, E |
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Primary Accession | P42892 |
Other Accession | P42893, Q4PZA2, P42891 |
Reactivity | Human |
Predicted | Bovine, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 87164 Da |
Antigen Region | 528-556 aa |
Gene ID | 1889 |
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Other Names | Endothelin-converting enzyme 1, ECE-1, ECE1 |
Target/Specificity | This ECE-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 528-556 amino acids of human ECE-1. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ECE-1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ECE1 |
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Function | Converts big endothelin-1 to endothelin-1. |
Cellular Location | Cell membrane; Single-pass type II membrane protein |
Tissue Location | All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma; isoforms A and C in liver, testis and small intestine; isoform B, C and D in endothelial cells and umbilical vein smooth muscle cells; isoforms C and D in saphenous vein cells, and isoform C in kidney |

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