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TCPR1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| FC, WB, IHC-P, E |
|---|---|
| Primary Accession | Q7Z6L1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 129696 Da |
| Antigen Region | 162-189 aa |
| Gene ID | 25851 |
|---|---|
| Other Names | Tectonin beta-propeller repeat-containing protein 1, TECPR1, KIAA1358 |
| Target/Specificity | This PALA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-189 amino acids from the N-terminal region of human TCPR1. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TCPR1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TECPR1 |
|---|---|
| Synonyms | KIAA1358 |
| Function | Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation. |
| Cellular Location | Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Scherer,S.W., et.al., Science 300 (5620), 767-772 (2003)
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$ 365.00
$ 140.00
Cat# AP6845a
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