FH Fumarase Monoclonal Antibody(2B11)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF |
---|---|
Primary Accession | P07954 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Calculated MW | 54637 Da |
Gene ID | 2271 |
---|---|
Other Names | Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) |
Dilution | WB~~WB: 1:1000-2000 |
Format | PBS, pH 7.4, containing 0.09% (W/V) sodium azide as Preservative and 50% Glycerol. |
Storage Conditions | -20℃ |
Name | FH {ECO:0000303|PubMed:27037871, ECO:0000312|HGNC:HGNC:3700} |
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Function | Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (PubMed:30761759). Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable). |
Cellular Location | [Isoform Mitochondrial]: Mitochondrion |
Tissue Location | Expressed in red blood cells; underexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Also acts as a tumor suppressor.
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