Anti-COVID-19 Nucleocapsid Protein Antibody
Rabbit polyclonal antibody to COVID-19 Nucleocapsid Protein
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, E |
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Primary Accession | P0DTC9 |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 45626 Da |
Gene ID | 43740575 |
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Other Names | Nucleoprotein; Nucleocapsid protein; NC; Protein N |
Target/Specificity | Recognizes COVID-19 Nucleocapsid Protein. |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | N {ECO:0000255|HAMAP-Rule:MF_04096} |
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Function | Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M (PubMed:33264373). Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions (PubMed:34901782, PubMed:36534661). |
Cellular Location | Virion {ECO:0000255|HAMAP-Rule:MF_04096}. Host cytoplasm Secreted. Host extracellular space. Note=Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding. When located inside the virion, complexed with the viral RNA Can be secreted by unconventional protein secretion (UPS) (PubMed:35921414). When secreted, can bind to host glycosaminoglycans on infected and non infected cells (PubMed:35921414). Found in host cytoplasmic stress granules (PubMed:34901782). {ECO:0000255|HAMAP- Rule:MF_04096, ECO:0000269|PubMed:34901782, ECO:0000269|PubMed:35921414} |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of COVID-19 Nucleocapsid Protein. The exact sequence is proprietary.
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