Anti-Myoglobin Antibody
Mouse monoclonal antibody to Myoglobin
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC |
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Primary Accession | P02144 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Calculated MW | 17184 Da |
Gene ID | 4151 |
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Other Names | Myoglobin |
Target/Specificity | Recognizes endogenous levels of Myoglobin protein. |
Dilution | IF~~IH (1/100 - 1/300) |
Format | Mouse IgG. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | MB (HGNC:6915) |
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Function | Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand (PubMed:30918256, PubMed:34679218). Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide (PubMed:32891753). Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity (PubMed:34679218). |
Cellular Location | Cytoplasm, sarcoplasm |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within human Myoglobin. The exact sequence is proprietary.
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