Anti-Beta-actin Antibody-HRP labled
Rabbit polyclonal antibody to Beta-actin-HRP labled
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P60709 |
Other Accession | P60710 |
Reactivity | Human, Mouse, Rat, Rabbit, Monkey, Chicken, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 41737 Da |
Gene ID | 60 |
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Other Names | Actin cytoplasmic 1; Beta-actin |
Target/Specificity | Recognizes endogenous levels of Beta-actin protein. |
Dilution | WB~~WB (1/2000 - 1/5000) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | ACTB |
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Function | Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (PubMed:25255767, PubMed:29581253). Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction (PubMed:29581253). In addition to their role in the cytoplasmic cytoskeleton, G- and F- actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA (PubMed:29925947). Part of the ACTR1A/ACTB filament around which the dynactin complex is built. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton. Nucleus Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence of human Beta-actin-HRP labled. The exact sequence is proprietary.
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