Anti-CD273 Antibody
Rabbit polyclonal antibody to CD273
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q9BQ51 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 30957 Da |
Gene ID | 80380 |
---|---|
Other Names | B7DC; CD273; PDCD1L2; PDL2; Programmed cell death 1 ligand 2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; CD273 |
Target/Specificity | Recognizes endogenous levels of CD273 protein. |
Dilution | WB~~WB (1/500 - 1/2000) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | PDCD1LG2 |
---|---|
Synonyms | B7DC, CD273, PDCD1L2, PDL2 |
Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). |
Cellular Location | [Isoform 3]: Secreted [Isoform 1]: Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9WUL5, ECO:0000305|PubMed:15340161} |
Tissue Location | Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD273. The exact sequence is proprietary.
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