Anti-DAB1 (pY220) Antibody
Rabbit polyclonal antibody to DAB1 (pY220)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | O75553 |
Other Accession | P97318 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 63775 Da |
Gene ID | 1600 |
---|---|
Other Names | Disabled homolog 1 |
Target/Specificity | Recognizes endogenous levels of DAB1 (pY220) protein. |
Dilution | WB~~WB (1/500 - 1/1000) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | DAB1 |
---|---|
Function | Signaling adapter of the reelin-mediated signaling pathway, which regulates the migration and differentiation of postmitotic neurons during brain development. Mediates intracellular transduction of Reelin signaling following reelin (RELN)-binding to its receptor: acts by docking proteins through its phosphotyrosine residues and PID domain. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P97318}. |
Tissue Location | Mainly expressed in brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DAB1 (pY220). The exact sequence is proprietary.
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